Currently, many women are postponing childbirth until they
are older for a variety of reasons. A new study has reported an advantage to
bearing children at an older age: increased longevity. The findings
were published online on June 23 in the journal Menopause.
Pregnant Woman at 40 years old |
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The investigators conducted a study to assess the
association between a woman’s age at birth of her last child and the likelihood
of survival to advanced age. They accessed data from the Long Life Family
Study. The study group comprised 311 women who survived past the oldest 5th
percentile of survival (cases) and 151 women who died at ages younger than the
top 5th percentile of survival (controls). A procedure known as a Bayesian
mixed-effect logistic regression model was used to estimate the relationship
between maternal age at birth of her last child and extraordinary longevity
among these 462 women.
The investigators found a significant association for older
maternal age: women who delivered their last child beyond age 33 years had
twice the odds for survival to the top 5th percentile of survival compared to
women who had their last child by age 29 years. They concluded that their study
supports findings from other studies that demonstrate a positive association
between older maternal age and greater odds for surviving to an unusually old
age.
Take home message:
Although this study reports increased longevity among women
who bear children at an older age, there is a down-side. The interval in which
the greatest likelihood of delivering a healthy child with the lowest risk of complications for both
mother and infant is age 20 to 30. Statistics are also better for women who
deliver their last child before the age 30. Women who deliver a child before 20
years of age have an increased risk of complications. The risk of pregnancy complications
such as preeclampsia (toxemia) and pregnancy-induced hypertension also
increases with age. In addition, the risk of delivering a child with birth defects increases
with age. For example, by age 35, a woman's risk of conceiving a child with
Down syndrome is about 1 in 350. By age 40, the risk is about 1 in 100, and by
age 45, the risk is about 1 in 30.
40 Year Mom Carry a Baby |
Healthy lifestyle choices also affect longevity. Lack of
exercise, overweight/obesity, smoking, and excessive alcohol intake impact
longevity. On a positive note, this study notes that older women who deliver a
normal, healthy child without complications have an increased likelihood of
surviving to a ripe old age. Obstetrical care has advanced to the point where older women who are
closely monitored during pregnancy have an excellent chance of a good outcome.
In addition, genetic testing can be done to check for birth defects.
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